Fig. 1

miR-454 increased the proliferation of MDA-MB-231 cells and improved the survival at ionizing radiation. a The miR-454 expression level was determined by qRT-PCR in MDA-MB-231 cells transfected with either miR-454 mimic or anti-miR-454 inhibitor. b The proliferation of MDA-MB-231 cells after transfection of miR-454 mimic. c The proliferation of MDA-MB-231 cells after transfection with anti-miR-454 inhibitor. d The proliferation of MDA-MB-231 cells after miR-454 overexpression at 20 Gy. e The proliferation of MDA-MB-231 cells after miR-454 overexpression at 40 Gy. f The proliferation of MDA-MB-231 cells after miR-454 overexpression at 60 Gy. All experiments were performed in triplicate