Drugs | Â | Total binding sites | Â | Â | (7JLT) NSP7-NSP8 of COVID-19 |
---|---|---|---|---|---|
Amprenavir | Known similar target molecule | Protease, HIV-1 | |||
Binding properties | 2 | 1 | Superposition type | L | |
RMSD | 1.09Â Ã… | ||||
Amino acid targets of drug | 184 LEU 130 VAL 132 ILE | ||||
No. of residues in known binding | 18 | ||||
Human similar targets | 5 | ||||
2 | Superposition type | R | |||
RMSD | 1.07Â Ã… | ||||
Amino acid targets of drug | 13 LEU 11 VAL 16 VAL 12 VAL | ||||
No. of residues in known binding | 18 | ||||
Human similar targets | 5 | ||||
Darunavir | Known similar target molecule | Protease, HIV-1 | |||
Binding properties | 1 | 1 | Superposition type | R | |
RMSD | 0.99Â Ã… | ||||
Amino acid targets of drug | 13 LEU 11 VAL 16 VAL | ||||
No. of residues in known binding | 20 | ||||
Human similar targets | 6 | ||||
Nelfinavir | Known similar target molecule | Protease, HIV-1 | |||
Binding properties | 1 | 1 | Superposition type | R | |
RMSD | 0.92Â Ã… | ||||
Amino acid targets of drug | 77 ASP 78 ASN 93 THR | ||||
No. of residues in known binding | 30 | ||||
Human similar targets | 10 | ||||
Rimantadine | Known similar target molecule | M2 protein, Influeza A | |||
Binding properties | 1 | 1 | Superposition type | L | |
RMSD | 0.96Â Ã… | ||||
Amino acid targets of drug | 83 VAL 86 ALA 85 SER | ||||
No. of residues in known binding | 10 | ||||
Human similar targets | 0 | ||||
Saquinavir | Known similar target molecule | Protease, HIV-1 | |||
Binding properties | 1 | 1 | Superposition type | R | |
RMSD | 0.97Â Ã… | ||||
Amino acid targets of drug | 160 VAL 183 PRO 185 ILE | ||||
No. of residues in known binding | 31 | ||||
Human similar targets | 5 |