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Table 2 DNA (%) presented in “head” and “tail” pre- and post-incubation with melphalan in breast cancer cell lines

From: Use of the comet assay technique for quick and reliable prediction of in vitro response to chemotherapeutics in breast and colon cancer

 

Control

Melphalan (1 μM )

 

% DNA

% DNA

% DNA

% DNA

(mean ± 1.96 S.E.)

(mean ± 1.96 S.E.)

(mean ± 1.96 S.E.)

(mean ± 1.96 S.E.)

 

in Head

in Tail

in Head

in Tail

MCF-7

66.43 ± 3.68

33.56 ± 3.68

83.96 ± 2.42

16.04 ± 2.35

MDA-MB 231

77.14 ± 2.98

22.85 ± 2.98

82.66 ± 2.33

17.34 ± 2.33

T47D

77.87 ± 2.60

22.12 ± 2.60

85.37 ± 1.93

14.62 ± 1.93