Table 5 CAD odds ratio associations with ACE I/D, Ang II AT2 receptor C3123A, and AGT M235T genotypes
From: Renin–angiotensin system gene polymorphisms among Saudi patients with coronary artery disease
OR | 95% CI | p value | |
|---|---|---|---|
ACE I/D genotypes | |||
ID vs II | 2.38 | (1.12-5.06) | 0.02 |
DD vs II | 2.45 | (1.26-4.78) | 0.008 |
DD vs ID | 1.03 | (0.60-1.78) | 0.914 |
DD vs ID and II | 1.40 | (0.88-2.23) | 0.15 |
DD and ID vs II | 2.43 | (1.27-4.64) | 0.007 |
Ang II AT2 (C3123A) genotypes | |||
CC vs CA | 3.45 | (2.03-5.92) | < 0.0001 |
CC vs AA | 0.01 | (0.001-0.18) | 0.001 |
CC vs CA and AA | 1.02 | (0.64-1.63) | 0.93 |
CC and AA vs CA | 7.21 | (4.31-12.04) | < 0.0001 |
AGT (M235T) genotypes | |||
MM vs MT | 0.95 | (0.54-1.67) | 0.86 |
MM vs TT | 0.79 | (0.43-1.46) | 0.46 |
TT vs MT | 1.20 | (0.70-2.06) | 0.51 |
MM vs MT and TT | 0.88 | (0.52-1.49) | 0.64 |
MM and TT vs MT | 1.08 | (0.68-1.71) | 0.74 |