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Table 1 Results of the modular enrichment analysis in the GeneCodis3 database

From: Identification and functional analysis of the BIM interactome; new clues on its possible involvement in Epstein–Barr Virus-associated diseases

Genes

NGR

TNGR

NG

TNG

Hyp

Hyp*

Annotations

6

107

34,208

6

7

5.67 × 10−15

2.84 × 10−14

Panther pathways P00006: Apoptosis signalling pathway

3

5

34,208

3

7

5.25 × 10−11

8.74 × 10−11

KEGG 04141: Protein processing in endoplasmic reticulum

KEGG 04722: Neurotrophin signalling pathway

KEGG 05200: Pathways in cancer

KEGG 05152: Tuberculosis

Panther pathways P00006: Apoptosis signalling pathway

KEGG 05210: Colorectal cancer

4

37

34,208

4

7

4.04 × 10−11

1.01 × 10−10

KEGG 05200: Pathways in cancer

Panther pathways P00006: Apoptosis signalling pathway

3

9

34,208

3

7

4.40 × 10−10

5.51 × 10−10

KEGG 05200: Pathways in cancer

KEGG 05014: Amyotrophic Lateral Sclerosis (ALS)

Panther pathways P00006: Apoptosis signalling pathway

KEGG 04210: Apoptosis

3

26

34,208

3

7

1.36 × 10−08

1.36 × 10−08

KEGG 05200: Pathways in cancer

KEGG 05145: Toxoplasmosis

Panther pathways P00006: Apoptosis signalling pathway

  1. p values have been obtained through Hypergeometric analysis corrected by the False Discovery Ratio (FDR) method. Annotations selected were KEGG and PANTHER pathways
  2. NGR number of annotated genes in the reference list, TNGR total number of genes in the reference list, NG number of annotated genes in the input list, TNG total number of genes in the input list, Hyp Hypergeometric p value, Hyp* corrected hypergeometric p value