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Table 1 Effect of hesperidin on DNAF, Ca2+and NO in rat testis of different studied groups

From: Protective role of hesperidin against γ-radiation-induced oxidative stress and apoptosis in rat testis

Groups DNAF as % in testes homogenate Ca2+ (mg ml−1) NO (µmol l−1)
In mitochondrial matrix
C 5.13 ± 0.50a 0.66 ± 0.066a 26.40 ± 2.77a
R 12.46 ± 1.20b 1.89 ± 0.19b 64.20 ± 7.45b
V 5.15 ± 0.25a 0.64 ± 0.067a 26.20 ± 2.60a
H 5.38 ± 0.51a 0.69 ± 0.074a 24.30 ± 2.24a
HR 6.10 ± 0.60c 0.97 ± 0.10c 31.50 ± 3.66c
RH 6.29 ± 0.60c 0.99 ± 0.10c 37.40 ± 3.53d
LSD 0.705 0.27 5.1
F value 211.6 230.8 166.5
  1. The values are expressed as mean ± SD. Values with different superscripts within the same column are statistically significant at p < 0.05. Number of rats in each group was 12. C group: Control group; R group: Rats were irradiated with γ-radiation (total dose: 8 Gy); H group: Rats were administered with 200 mg of hesperidin (H) kg−1 body mass (b.m.), since H was dissolved in 1 ml of 99.6% DMSO; V group: Rats were administered with 1 ml of 99.6% DMSO kg−1 (b.m); HR group: Rats were treated with the same dose of H before their irradiation with the same dose of γ-radiation; RH group: Rats were irradiated with the same dose of γ-radiation then they treated with the same dose of H