MicroRNA expression profile of urinary exosomes in Type IV lupus nephritis complicated by cellular crescent

Table 2 Fifteen signalling pathways affected in LVIN-CC

KEGG pathway	p value	N genes	N miRNAs
Wnt signalling pathway	0.00020396	100	59
Signalling pathways regulating pluripotency of stem cells	0.001959962	95	57
Focal adhesion	0.002590298	138	56
Hippo signalling pathway	3.53E−05	107	54
Neurotrophin signalling pathway	0.009351432	81	54
Axon guidance	1.45E−05	94	52
FoxO signalling pathway	0.00541505	92	52
Ubiquitin-mediated proteolysis	0.006921462	91	49
ErbB signalling pathway	0.000164182	67	49
TGF-beta signalling pathway	0.004491223	53	48
Arrhythmogenic right ventricular cardiomyopathy	0.00042872	51	46
Lysine degradation	0.00109878	34	46
N-Glycan biosynthesis	0.009852971	34	39
Other types of O-glycan biosynthesis	0.034708487	20	32
Fatty acid biosynthesis	3.53E−05	8	11

These pathways were identified from the intersection of the DIANA-mirPath results of three databases (TargetScan, Tarbase7.0, and microT-CDS v5.0) with exclusion of tumour, hepatitis B, leukaemia, and thyroid hormone-related pathways

ISSN: 2241-5793