Doxorubicin (μg ml−1) | Induction of apoptosis | Total cells | Micronucleus Induction | ||||
---|---|---|---|---|---|---|---|
Total cells | Live cells (%) Mean ± SE | Apoptotic cells (%) Mean ± SE | Cells with MN (%) Mean ± SE | CBPI | Cytotoxicity (%) Mean ± SE | ||
0 | 9262 | 8507 92.43 ± 2.55 | 748 7.5 ± 2.51 | 5122 | 55 1.1 ± 0.19 | 1.55 ± 0.07 | – |
0.5 | 10,614 | 4260 39.83 ± 4.48 | 6220 58.88* ± 4.35 | 2329 | 47 3.86* ± 1.87 | 1.22 ± 0.03 | 60.01 ± 3.35 |
2 | 10,673 | 1417 12.95 ± 2.81 | 8587 80.51* ± 0.56 | 483 | 8 1.3 ± 0.39 | 1.28 ± 0.07 | 50.61 ± 9.77 |