Fig. 3

Relative changes of lymphocytes out of milk and blood related to the used MucoCD-I vaccine batches. The percentage variations of lymphocyte contents per group [(“Ctr” control animals (n = 5), “LR” treated, low responder animals (n = 4), “HR” treated, high responder animals (n = 5)] and per milk and blood are represented as LSM ± SD on the vertical axes. The comparative indices are the treatment weeks (TW) before the first-time application of the vaccine batches A or B, respectively. The upper abscissa shows the used routes for administration of the vaccine [nasal (N), percutaneous (PC), subcutaneous (SC) and intracutaneous (IC)] marking the dates of immunization (IM), too. The MucoCD-I was given only once plus incomplete Freund’s adjuvant (iFA) in TW 31. In TWs 3 and TW 17, the primal injections of the vaccine batches A or B are accented by the gray bars. Deviated by group, the asterisks (p < 0.05) indicate considerable differences relating to the dates immediately before the first use of each vaccine batch. The significant variations (p < 0.05) between the groups at the same times are characterized by small letters (a, b, c)