Fig. 5

Tan IIA alleviated the inductive effect of Aβ on the expression of inflammatory factors in SH-SY5Y cells. SH-SY5Y cells were preconditioned with Tan IIA (5 or 10 μM) for 1 h followed by treatment with Aβ (25 μM) for 48 h. a–c ELISA assay examined the concentration of TNF-α, IL-1β and IL-6 in the culture supernatant. d–f qRT-PCR analysis evaluated the mRNA levels of TNF-α, IL-1β and IL-6 in SH-SY5Y cells. *p < 0.05, **p < 0.01 vs. respective control