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Fig. 1 | Journal of Biological Research-Thessaloniki

Fig. 1

From: Genome wide meta-analysis of cDNA datasets reveals new target gene signatures of colorectal cancer based on systems biology approach

Fig. 1

MA plots of an individual quality array after normalization. M and A is specified as \( \text{M}\,\text{ = }\,\text{log}_{2} \,\left( {\text{I}_{1} } \right)\, - \,\text{log}_{2} \,\left( {\text{I}_{2} } \right),\,\text{A}\,\text{ = }\,\text{1/2}\,\,\left( {\text{log}_{2} \,\left( {\text{I}_{1} } \right)\, - \,\text{log}_{2} \,\left( {\text{I}_{2} } \right)} \right) \), where I1 is the intensity of the array studied, and I2 is the intensity of a “pseudo”-array that consists of the median across arrays”. Normally, the mass of distribution in the MA plot is expected to be concentrated along the M = 0 axis with no trend in M as a function of A

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