Fig. 5
Elevated expression of CCND2 AS1 suppressed tumor growth in vivo. a Images of tumors formed in the nude mice injected with the indicated cells. The control or HeLa-pCCND2 AS1 were injected into the right flanks (n = 5), respectively. b, cCCND2 AS1 up-regulated significantly inhibited tumor growth in tumor weights and sizes in nude mice. Tumor volumes were calculated by the formula: V = 0.5 × L × W2 after injection every week. Bars indicate SD. Asterisk(s) indicates a significant change (*p < 0.05, **p < 0.01). Data are the mean ± SD