Fig. 5
From: LncRNA NCK1-AS1 in plasma distinguishes oral ulcer from early-stage oral squamous cell carcinoma
NCK1-AS1 promoted OSCC cell migration and invasion through miR-100. Transwell invasion and migration data analyzed by one-way ANOVA and Tukey test showed that overexpression of NCK1-AS1 resulted in a significantly increased rate of invasion (a) and migration (b) in comparison to C and NC groups. Overexpression of miR-100 played an opposite role and attenuated the effects of overexpression of NCK1-AS1 (*p < 0.05). MSP was performed to analyze the effects of overexpression of NCK1-AS1 on the methylation of miR-100 in both SCC25 and SCC090 cells. Experiments were repeated 3 times and representative images were presented (c)