Fig. 1

a Schematic of the therapeutic triple complex in blood circulation. b RBC–NPs complexes detach from RBCs in small capillaries, this process increases the rACE2 in lung capillaries and saving cellular rACE2 activity. c Also, it acts as a decoy for 2019-nCoV and decrease viral spreading. The therapeutic triple complex acts as a bioreactor in the blood circulation and decreases serum level of Ang II with cleavage it to Ang 1–7