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Table 3 Expression of cell adhesion molecules ICAM-1 and HCAM (CD44s) in malignant carcinomas

From: Cell adhesion molecules’ altered profile in benign and malignant salivary gland tumors. The paradigm of beta4-integrin, desmoglein-2, ICAM-1 and CD44s

Type of tumor ICAM-1 HCAM (CD44s)
Positivity Pattern Intensity Positivity Pattern Intensity
ACC (n = 7) III (1)
I (6)
M
M (3), M (luminal surface) (3)
+++
++
III M +++
EMYC (n = 3) II (2)
I (1)
M (luminal cells/surface)
M (non-luminal cells)
++ I M
(non-luminal cells)
+++
ADCC (n = 3) (-) (2), I (1) M ++ III M ++
PLGA (n = 2) II M (luminal surface of luminal cells) ++ II M (luminal central cells) +++
MEC (n = 3) II M ++ III M(epithelioid/intermediate cells) +++
SDC (n = 3) III (2)
I % (1)
C
M/C
++
+++
III (1)
I (2)
M +++
++
SCC (n = 5) High grade (2)
Low grade (3)
I
III (1), I (2)
M ++ I
III
M +
+++
LEPC (n = 2) I (1), II (2) M +++ I (1), II (2) M ++ , +++
ONC (n = 1) 0 M ++ II M ++
MYEC (n = 1) I M ++ III M ++
ANOS (n = 1) III M ++ 0 M/C +
  1. ΑCC Acinic cell carcinoma, EMYC Epithelial-myoepithelial carcinoma, ADCC Adenoid cystic carcinoma, PLGA Polymorphous low-grade adenocarcinoma, MEC Mucoepidermoid carcinoma, SDC Salivary ductal carcinoma, SCC Squamous cell carcinoma, LEPC Lymphoepithelial carcinoma, ONC Oncocytic carcinoma, MYEC Myoepithelial carcinoma, ANOS Adenocarcinoma not otherwise specified, n Number of cases, M Membranous, C Cytoplasmic