Fig. 5

MiR-363-3p directly targeted CXCL5. a The binding sites between CXCL5 3′UTR and miR-363-3p were exhibited. The interaction between CXCL5 and miR-363-3p was confirmed by dual-luciferase reporter assay (b, c) and RNA immunoprecipitation assay (d, e). f–h SW620 and SW480 cells were transfected with si-con, si-circCTNNA1#2, si-circCTNNA1#2 + in-miR-con or si-circCTNNA1#2 + in-miR-363-3p. The protein expression of CXCL5 was detected by WB analysis. *** p < 0.001