Table 5 Drug targets of identified differentially expressed genes
Gene | Drugs | Drug Bank ID | FDA approval |
|---|---|---|---|
PDZK1 | Afimoxifene | DB04468 | Investigational |
PDZK1 | Raloxifene hydrochloride | DB00481 | Investigational |
PDZK1 | Urethane | DB04827 | Removed |
PDZK1 | Valproic acid | DB00313 | Approved |
PDZK1 | Ciglitazone | DB09201 | Experimental |
PDZK1 | Estradiol | DB00783 | Approved |
PDZK1 | Fenofibric acid | DB13873 | Approved |
PDZK1 | Ormosil | DB00742 | Approved |
PDZK1 | Polyethylene glycols | DB09287 | Approved |
PDZK1 | Zoledronic acid | DB00399 | Approved |
ID4 | Acetaminophen | DB00316 | Approved |
ID4 | Belinostat | DB05015 | Approved |
ID4 | Dorsomorphin | DB08597 | Experimental |
ID4 | Doxorubicin | DB00997 | Approved |
ID4 | Estradiol | DB00783 | Approved |
ID4 | Panobinostat | DB06603 | Approved |
ID4 | Tamoxifen | DB00675 | Approved |
ID4 | Valproic acid | DB00313 | Approved |
RHEB | Cisplatin | DB00515 | Approved |
RHEB | Lonafarnib | DB06448 | Investigational |
RHEB | Tipifarnib | DB04960 | Investigational |
SLPI | Copper | DB09130 | Approved |
SLPI | Ormosil | DB00742 | Approved |
SLPI | Polyethylene glycols | DB09287 | Approved |
SLPI | Doxorubicin | DB00997 | Approved |
SLPI | Cyclosporine | DB00091 | Approved |
SLPI | Cisplatin | DB00515 | Approved |
SLPI | Aspirin | DB00945 | Approved |
AKR1C2 | Aspirin | DB00945 | Approved |
AKR1C2 | Cloxazolam | DB01553 | Experimental |
AKR1C2 | Diazepam | DB00829 | Approved |
AKR1C2 | Estazolam | DB01215 | Approved |
AKR1C2 | Flurbiprofen | DB00712 | Approved |
AKR1C2 | Glipizide | DB01067 | Approved |
AKR1C2 | Indomethacin | DB00328 | Approved |
AKR1C2 | Meclofenamic acid | DB00939 | Approved |
NCOA1 | Tamoxifen | DB00675 | Approved |
NCOA2 | Calcitriol | DB00136 | Approved |
NCOA3 | Rifampin | DB01045 | Approved |
NCOA4 | Troglitazone | DB00197 | Approved |
NCOA5 | Alitretinoin | DB00523 | Approved |
PLAUR | Urokinase | DB00013 | Approved |
PLAUR | Tenecteplase | DB00031 | Approved |
PLAUR | Anistreplase | DB00029 | Approved |
PLAUR | Filgrastim | DB00099 | Approved |
PLAUR | Interferon gama-1b | DB00011 | Approved |
PLAUR | Reteplase | DB00015 | Approved |
PLAUR | Alteplase | DB00009 | Approved |
ANXA1 | Desonide | DB01260 | Approved |
ANXA1 | Prednisone | DB00635 | Approved |
ANXA1 | Trastuzumab | DB00072 | Approved |
ANXA1 | Loteprednol etabonate | DB14596 | Approved |
ANXA1 | Desoximetasone | DB00547 | Approved |
ANXA1 | Hydrocortisone | DB00741 | Approved |
ANXA1 | Hydrocortamate | DB00769 | Approved |
ANXA1 | Triamcinolone | DB00620 | Approved |
ANXA1 | Prednisolone | DB00860 | Approved |
ANXA1 | Amcinonide | DB00288 | Approved |
ANXA1 | Flumethasone pivalate | DB00663 | Approved |
ANXA1 | Betamethasone | DB00443 | Approved |
ANXA1 | Methylprednisolone | DB00959 | Approved |
ANXA1 | Rimexolone | DB00896 | Approved |
ANXA1 | Halobetasol propionate | DB00596 | Approved |
ANXA1 | Dexamethasone | DB01234 | Approved |
ANXA1 | Prednicarbate | DB01130 | Approved |