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Fig. 2 | Journal of Biological Research-Thessaloniki

Fig. 2

From: CircCNIH4 inhibits gastric cancer progression via regulating DKK2 and FRZB expression and Wnt/β-catenin pathway

Fig. 2

Overexpression of circCNIH4 suppressed gastric cancer cells progression via inactivating Wnt/β-catenin pathway. MKN-74 and HGC-27 cells were transfected with circCNIH4 overexpression vector or NC vector. a and b The expression of circCNIH4 was detected by qRT-PCR in MKN-74 and HGC-27 cells. c the protein level of β-catenin was measured by western blot in MKN-74 and HGC-27 cells. d and e Proliferation of MKN-74 and HGC-27 cells was determined by MTT assay. f The protein level of Ki67 was measured by western blot in MKN-74 and HGC-27 cells. g Apoptosis of MKN-74 and HGC-27 cells was detected by flow cytometry assay. h and i Migration and invasion of MKN-74 and HGC-27 cells were assessed by transwell assay. *p < 0.05

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