Fig. 6

Overexpression of circCNIH4 inhibited tumor growth in gastric cancer in vivo. MKN-74 cells transfected with circCNIH4 or NC (empty vectors) were subcutaneously injected into nude mice. a Tumor volume was measured every 4 days after implantation for 14 days. b Tumor weight was measured at 34 days after implantation. c The expression of circCNIH4 was detected by qRT-PCR. d and e The protein levels of DKK2 and FRZB were detected by western blot. *p < 0.05