Fig. 1

Hsa_circ_0000231 was overexpressed in CRC tissues and cells with poor prognosis of CRC patients. A, D Hsa_circ_0000231 expression was detected by qRT-PCR in 47 pairs of CRC and matched healthy colorectal tissues as well as NCM460, HCT116 and SW620 cells. B The overall survival curve of CRC sufferers with high or low hsa_circ_0000231 expression was assessed by Kaplan–Meier methods. C RNase R treatment assay was employed to demonstrate hsa_circ_0000231 was more stable than linear mRNA. *p < 0.05 (Wilcoxon rank-sum test, two-tailed Student’s t-tests and ANOVA with Tukey’s test)