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Fig. 7 | Journal of Biological Research-Thessaloniki

Fig. 7

From: LncRNA FBXL19-AS1 promotes proliferation and metastasis of cervical cancer through upregulating COL1A1 as a sponge of miR-193a-5p

Fig. 7

miR-193a-5p targeted COL1A1. The downstream pathways modulated by miR-193a-5p was analyzed via mirPath v.3 (http://snf-515788.vm.okeanos.grnet.gr/index.php?r=mirpath). B TargetScan database (http://www.targetscan.org/vert_72/) was used for predicting the binding sites between miR-193a-5p and COL1A1. C RT-PCR was performed to test COL1A1 expression in CC tissues. D The diagnostic significance of COL1A1 in CC was analyzed via KM plotter (http://kmplot.com/analysis/). E The expression of COL1A1 in normal cervical tissues and cervical cancer tissues was analyzed in The Human Protein Alas (https://www.proteinatlas.org/). F luciferase reporter gene experiment was conducted to confirm the targeting relationship between miR-193a-5p and COL1A1. G, H Western blot was used for the detection of COL1A1 in CC cells with gain and loss of miR-193a-5p (G) and FBXL19-AS1 (H) expression. ns p > 0.05, **p < 0.01, ***p < 0.001 (n = 3)

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