Fig. 8

Inhibition of COL1A1 attenuated CC cell proliferation and metastasis. A C-33 A cells were transfected with si-NC or si-COL1A1 and Western blot was used for the detection of COL1A1 protein expression; B CCK-8 assay was taken to measure cell proliferation changes after COL1A1 knockdown, *p < 0.05 and **p < 0.01 vs. si-NC group; C Apoptosis protein expression after COL1A1 knockdown treatment was evaluated by western blot; D, E Transwell was applied to detect the ability of cancer cell migration and invasion after COL1A1 knockdown; F Western blot was taken to measure the expression of relevant EMT-related markers after COL1A1 knockdown. *p < 0.05