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Fig. 4 | Journal of Biological Research-Thessaloniki

Fig. 4

From: Peroxiredoxin-6 regulates p38-mediated epithelial–mesenchymal transition in HCT116 colon cancer cells

Fig. 4

Prx6 regulates p38-mediated EMT-related genes. A Western blotting of MAPKs—p38, ERK, and JNK—in HCT116 cells in the presence or absence of Prx6. B The MAPK inhibitors were used in Prx6 downregulated HCT116 cells to detect the rescue of EMT-transcription factors and protein markers. Western blotting was used for detecting relative protein expressions. C The MAPK protein level was detected from tumor tissues via Western blotting. Graphs represent the quantification of Western blot band intensity. Data are expressed as mean ± SD (n = 3). *p < 0.05, **p < 0.01, and ***p < 0.001

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