Fig. 8

Schematic diagram of working mechanism behind the oncogenic role of circ_0000620 in GC cells. Circ_0000620 competitively combined with miR-671-5p to increase the MMP2 expression, thereby promoting GC cell proliferation, metastasis and angiogenesis. Additional file 1; Fig. S1. Circ_0000620 was the most significantly upregulated in 5 GC samples. The levels of circ_0000620, circ_0000847 and circ_0000567 were detected by qRT-PCR in 5 pairs of GC and normal tissues. Three repetitions were performed in the qRT-PCR experiment, with three parallels every time. *p < 0.05