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Table 2 Pathway enrichment analysis of potential biomarkers using Enrich tool

From: A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia

Pathway identifier Pathway name Entities found Entities total Entities ratio Entities p-value Entities FDR Reactions found Reactions total Reactions ratio
R-HSA-3772470 Negative regulation of TCF-dependent signaling by WNT 1 15 0.00172 0.00686 0.05726 1 5 5.96E−04
R-HSA-5173214 O-glycosylation of TSR domain-containing proteins 1 39 0.00447 0.01776 0.05726 2 2 2.38E−04
R-HSA-977225 Amyloid formation 1 57 0.00653 0.02588 0.05726 2 14 0.001668653
R-HSA-5173105 O-linked glycosylation 1 104 0.01192 0.04684 0.05726 2 18 0.002145411
R-HSA-392499 Metabolism of proteins 2 916 0.10501 0.05726 0.05726 4 443 0.052800954
R-HSA-201681 TCF dependent signaling in response to WNT 1 198 0.02270 0.08775 0.08775 1 71 0.008462455
R-HSA-195721 Signaling by Wnt 1 294 0.03370 0.12815 0.12815 1 153 0.018235995
R-HSA-597592 Post-translational protein modification 1 416 0.04769 0.1775 0.17754 2 197 0.023480334
R-HSA-162582 Signal transduction 1 2411 0.27640 0.72584 0.72584 1 1693 0.201787843