A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia

Table 2 Pathway enrichment analysis of potential biomarkers using Enrich tool

Pathway identifier	Pathway name	Entities found	Entities total	Entities ratio	Entities p-value	Entities FDR	Reactions found	Reactions total	Reactions ratio
R-HSA-3772470	Negative regulation of TCF-dependent signaling by WNT	1	15	0.00172	0.00686	0.05726	1	5	5.96E−04
R-HSA-5173214	O-glycosylation of TSR domain-containing proteins	1	39	0.00447	0.01776	0.05726	2	2	2.38E−04
R-HSA-977225	Amyloid formation	1	57	0.00653	0.02588	0.05726	2	14	0.001668653
R-HSA-5173105	O-linked glycosylation	1	104	0.01192	0.04684	0.05726	2	18	0.002145411
R-HSA-392499	Metabolism of proteins	2	916	0.10501	0.05726	0.05726	4	443	0.052800954
R-HSA-201681	TCF dependent signaling in response to WNT	1	198	0.02270	0.08775	0.08775	1	71	0.008462455
R-HSA-195721	Signaling by Wnt	1	294	0.03370	0.12815	0.12815	1	153	0.018235995
R-HSA-597592	Post-translational protein modification	1	416	0.04769	0.1775	0.17754	2	197	0.023480334
R-HSA-162582	Signal transduction	1	2411	0.27640	0.72584	0.72584	1	1693	0.201787843

ISSN: 2241-5793