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  1. Gastric cancer (GC) is one of the most common cancers in the digestive system. Circular RNAs (circRNAs) have been found to function as important regulators in the pathogenesis of GC. This study focused on the ...

    Authors: Junyu Ren, Guoqing Pan, Jun Yang, Ning Xu, Qiong Zhang and Wenliang Li
    Citation: Journal of Biological Research-Thessaloniki 2021 28:23
  2. Peroxiredoxins (Prxs) are antioxidant enzymes that protect cells from oxidative stress induced by several factors. They regulate several signaling pathways, such as metabolism, immune response, and intracellul...

    Authors: Unbin Chae, Bokyung Kim, HanSeop Kim, Young-Ho Park, Seung Hwan Lee, Sun-Uk Kim and Dong-Seok Lee
    Citation: Journal of Biological Research-Thessaloniki 2021 28:22
  3. Cervical cancer (CC) is one of the most common and malignant tumors in women. In this study, we aim to explore the role and mechanism of F-box and leucine rich repeat protein 19 antisense RNA 1 (FBXL19-AS1), a...

    Authors: Xiaoyong Huang, Haiyan Shi, Xinghai Shi and Xuemei Jiang
    Citation: Journal of Biological Research-Thessaloniki 2021 28:20
  4. Circular RNAs (circRNAs) have been reported to play an important role in tumor progression in various cancer types, including gastric cancer. The aim of this study was to investigate the role of circCNIH4 (hsa...

    Authors: Qi Shi, Chuanwen Zhou, Rui Xie, Miaomiao Li, Peng Shen, Yining Lu and Shijie Ma
    Citation: Journal of Biological Research-Thessaloniki 2021 28:19
  5. Novel Coronavirus disease 2019 or COVID-19 has become a threat to human society due to fast spreading and increasing mortality. It uses vertebrate hosts and presently deploys humans. Life cycle and pathogenici...

    Authors: Umesh C. Halder
    Citation: Journal of Biological Research-Thessaloniki 2021 28:18
  6. Although the cellulose microfibril organization in guard cell (GC) walls play a crucial role in the mechanism of the stomatal function, recent work showed that matrix cell wall materials are also involved. Esp...

    Authors: Panagiotis Apostolakos, Eleni Giannoutsou and Basil Galatis
    Citation: Journal of Biological Research-Thessaloniki 2021 28:17
  7. α-Thalassemia, a congenital hemoglobinopathy, is characterized by deficiency and/or reduced levels of α-globin chains in serious forms of α-thalassemia (HbH disease/Hb Bart’s). This research work deals with a ...

    Authors: Androulla N. Miliotou, Dionysia Papagiannopoulou, Efthymia Vlachaki, Martina Samiotaki, Dimitra Laspa, Stamatia Theodoridou, Asterios S. Tsiftsoglou and Lefkothea C. Papadopoulou
    Citation: Journal of Biological Research-Thessaloniki 2021 28:16
  8. E proteins are transcriptional regulators that regulate many developmental processes in animals and lymphocytosis and leukemia in Homo sapiens. In particular, E2A, a member of the E protein family, plays a major ...

    Authors: Jia-Jie Liang, Hu Peng, Jiao-Jiao Wang, Xiao-Hui Liu, Lan Ma, Yi-Ran Ni, Huai-Jie Yang, Yan-Qiong Zhang, Wen-Bing Ai and Jiang-Feng Wu
    Citation: Journal of Biological Research-Thessaloniki 2021 28:15
  9. Sevoflurane (Sev), a commonly used volatile anesthetic, has been reported to inhibit the process of colorectal cancer (CRC). Circular RNAs (circRNAs) are revealed to participate in the pathogenesis of CRC. Thi...

    Authors: Jingpeng Wang, Shuyuan Li, Gaofeng Zhang and Huihua Han
    Citation: Journal of Biological Research-Thessaloniki 2021 28:14
  10. Cortical microtubules regulate cell expansion by determining cellulose microfibril orientation in the root apex of Arabidopsis thaliana. While the regulation of cell wall properties by cortical microtubules is we...

    Authors: Veronica Giourieva and Emmanuel Panteris
    Citation: Journal of Biological Research-Thessaloniki 2021 28:13
  11. The Indo-Pacific sea urchin Diadema setosum has invaded the Mediterranean Sea and has spread along many locations in the southeastern part of the basin, where established populations exist on the shallow subtidal...

    Authors: Dimitris Vafidis, Chryssanthi Antoniadou, Konstantinos Voulgaris, Anastasios Varkoulis and Chrysoula Apostologamvrou
    Citation: Journal of Biological Research-Thessaloniki 2021 28:11
  12. Lipoxygenases are one of the critical signaling mediators which can be targeted for human prostate cancer (PC) therapy. In this study, 4-methyl-2-(4-methylpiperazinyl)pyrimido[4,5-b]benzothiazine (4-MMPB) and ...

    Authors: Sonia Iranpour, Aseel Kamil Mohammed Al-Mosawi, Ahmad Reza Bahrami, Hamid Sadeghian and Maryam M. Matin
    Citation: Journal of Biological Research-Thessaloniki 2021 28:10
  13. Microcystins are emerging marine biotoxins, produced by potentially toxic cyanobacteria. Their presence has been reported in aquatic animals in Greek freshwater, while data are few in marine environments. Sinc...

    Authors: Maria P. Kalaitzidou, Christina I. Nannou, Dimitra A. Lambropoulou, Konstantinos V. Papageorgiou, Alexandros M. Theodoridis, Vangelis K. Economou, Ioannis A. Giantsis, Panagiotis G. Angelidis, Spyridon K. Kritas and Evanthia J. Petridou
    Citation: Journal of Biological Research-Thessaloniki 2021 28:8
  14. Circular RNAs (circRNA) have been shown to be involved in the pathogenesis of colorectal cancer (CRC). CircCTNNA1 was found to be one of the upregulated circRNAs in CRC. However, there are few studies on circC...

    Authors: Yan Zhang, Sheng Zheng, Nansheng Liao, Huifeng Huang, Wenxiao Chen, Zhenxing Wu and Deqing Wu
    Citation: Journal of Biological Research-Thessaloniki 2021 28:7
  15. Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease. The oxidative stress is an important component of the pathogenesis of PD. Artemisinin (ART) has antioxida...

    Authors: Junqiang Yan, Hongxia Ma, Xiaoyi Lai, Jiannan Wu, Anran Liu, Jiarui Huang, Wenjie Sun, Mengmeng Shen and Yude Zhang
    Citation: Journal of Biological Research-Thessaloniki 2021 28:6
  16. Because of the highly heterogeneous nature of breast cancer, each subtype differs in response to several treatment regimens. This has limited the therapeutic options for metastatic breast cancer disease requir...

    Authors: Reem Altaf, Humaira Nadeem, Mustafeez Mujtaba Babar, Umair Ilyas and Syed Aun Muhammad
    Citation: Journal of Biological Research-Thessaloniki 2021 28:5
  17. One third of the worldwide amphibian species are threatened, therefore, efficient monitoring efforts are needed. Amphibians which adopt a hidden lifestyle, such as the common spadefoot toad, are often missed w...

    Authors: Lukas Landler and Katharina Stefke
    Citation: Journal of Biological Research-Thessaloniki 2021 28:4
  18. Amniote vertebrates share a suite of extra-embryonic membranes that distinguish them from anamniotes. Other than that, however, their reproductive characteristics could not be more different. They differ in ba...

    Authors: Shai Meiri, Gopal Murali, Anna Zimin, Lior Shak, Yuval Itescu, Gabriel Caetano and Uri Roll
    Citation: Journal of Biological Research-Thessaloniki 2021 28:3
  19. Erythroleukemia is caused by the uncontrolled multiplication of immature erythroid progenitor cells which fail to differentiate into erythrocytes. By directly targeting this class of malignant cells, the induc...

    Authors: Christos I. Papagiannopoulos, Nikoleta F. Theodoroula, Konstantinos A. Kyritsis, Melpomeni G. Akrivou, Maria Kosmidou, Konstantina Tsouderou, Nikolaos Grigoriadis and Ioannis S. Vizirianakis
    Citation: Journal of Biological Research-Thessaloniki 2021 28:2
  20. Circ_0000396 was found to be down-regulated in the rheumatoid arthritis (RA) patients and had a high diagnostic value. However, the function and mechanisms underlying circ_0000396 in RA progression remain uncl...

    Authors: Laifang Wang, Qing Zhao, Na Wang, Yanjie Ding, Lingli Kong and Jing Wang
    Citation: Journal of Biological Research-Thessaloniki 2021 28:1
  21. Prostate cancer (PC) is the most prevalent type of cancer in men worldwide. In Saudi Arabia, the rate of PC is increasing annually. The sex steroid hormones androgens and their receptors have critical roles in...

    Authors: Yousef MohammedRabaa Hawsawi, Samar Abdullah Zailaie, Atif Abdulwahab A. Oyouni, Othman Rashed Alzahrani, Osama Mohamed Alamer and Saad Ali S. Aljohani
    Citation: Journal of Biological Research-Thessaloniki 2020 27:20
  22. Alterations in intercellular and cell-extracellular matrix connections contribute to tumour development. This study investigates the expression of specific cell adhesion molecules (CAMs) in salivary gland tumo...

    Authors: Dimitrios Andreadis, Athanasios Poulopoulos, Apostolos Epivatianos, Alexandros Nomikos, Dimitrios Parlitsis, Konstantinos Christidis, Calypso Barbatis, Dimitrios Kavvadas, Alexandros Toskas, Theodora Papamitsou and Dimitrios Antoniades
    Citation: Journal of Biological Research-Thessaloniki 2020 27:18
  23. A novel infectious disease, caused by 2019 Novel Coronavirus (2019-nCoV) is responsible for the recent outbreak of severe respiratory disease. The 2019-nCoV spread rapidly and reaching epidemic proportions in ...

    Authors: Zahra Sadat Aghili, Seyed Abbas Mirzaei and Mehdi Banitalebi-Dehkordi
    Citation: Journal of Biological Research-Thessaloniki 2020 27:17
  24. Oral squamous cell carcinoma (OSCC) at early stages can be misdiagnosed as an oral ulcer (OU) due to similar symptoms, such as chronic and indurated ulcer. LncRNA NCK1-AS1 has been characterized as a key playe...

    Authors: Fei Le, Yangqian Ou, Ping Luo and Xiaoming Zhong
    Citation: Journal of Biological Research-Thessaloniki 2020 27:16
  25. The present study aims to investigate, immunohistochemically, the role of the adaptive immune response in cardiac arrest/resuscitation-induced ischemia–reperfusion renal injury (IRI), namely to assess the pres...

    Authors: Maria Tsivilika, Eleni Doumaki, George Stavrou, Antonia Sioga, Vasilis Grosomanidis, Soultana Meditskou, Athanasios Maranginos, Despina Tsivilika, Dimitrios Stafylarakis, Katerina Kotzampassi and Theodora Papamitsou
    Citation: Journal of Biological Research-Thessaloniki 2020 27:15
  26. The discovery of neural precursor cells (NPCs) and the concomitant intensive research in the field offer regenerative medicine novel approaches, enabling it to tackle conditions, such as neurodegenerative dise...

    Authors: Ioannis Paspaltsis, Evangelia Kesidou, Olga Touloumi, Roza Lagoudaki, Marina Boziki, Martina Samiotaki, Dimitra Dafou, Theodoros Sklaviadis and Nikolaos Grigoriadis
    Citation: Journal of Biological Research-Thessaloniki 2020 27:14
  27. Toll-like receptor 4 (TLR4) plays an important role in the elimination of Gram-negative bacteria infections and the initiation of antiinflammatory response. Using the technology of pronuclear microinjection, g...

    Authors: Xiaofei Guo, Jinlong Zhang, Yao Li, Jing Yang, Yihai Li, Chunxiao Dong, Guoshi Liu, Zhengxing Lian and Xiaosheng Zhang
    Citation: Journal of Biological Research-Thessaloniki 2020 27:13
  28. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Umair Ilyas, Shahiq uz Zaman, Reem Altaf, Humaira Nadeem and Syed Aun Muhammad
    Citation: Journal of Biological Research-Thessaloniki 2020 27:12

    The original article was published in Journal of Biological Research-Thessaloniki 2020 27:8

  29. Long non-coding RNA (lncRNA) plays an important role in tumorigenesis. The lncRNA CCND2 AS1 has been shown to be involved in the growth of several tumors; however, its role in cervical cancer has not been elucida...

    Authors: Chengcheng Zhao, Jian Liu, Huazhang Wu, Jiaojiao Hu, Jianquan Chen, Jie Chen and Fengchang Qiao
    Citation: Journal of Biological Research-Thessaloniki 2020 27:11
  30. Biofilm formation is a complex phenomenon of bacterial cells, involved in several human infections. Its formation is regulated and controlled by several protein factors. The BolA-like proteins (bolA gene) are con...

    Authors: Mohd W. Azam, Azna Zuberi and Asad U. Khan
    Citation: Journal of Biological Research-Thessaloniki 2020 27:10
  31. Neoplasia is a multilevel condition caused by irregularities over the genome, which can lead to a fatal result. To fully understand this phenomenon, an evolutionary challenge has risen during the last decades,...

    Authors: Christos V. Kitsoulis, Athanasios D. Baxevanis and Theodore J. Abatzopoulos
    Citation: Journal of Biological Research-Thessaloniki 2020 27:9
  32. Colorectal cancer is known to be the most common type of cancer worldwide with high disease-related mortality. It is the third most common cancer in men and women and is the second major cause of death globall...

    Authors: Umair Ilyas, Shahiq uz Zaman, Reem Altaf, Humaira Nadeem and Syed Aun Muhammad
    Citation: Journal of Biological Research-Thessaloniki 2020 27:8

    The Correction to this article has been published in Journal of Biological Research-Thessaloniki 2020 27:12

  33. Members of Tumor Necrosis Factor (TNF) Receptor-Associated Factors (TRAFs) family interact with the cytoplasmic tails of TNF receptor family members to mediate signal transduction processes. TRAF3 has a major ...

    Authors: George Kotsaris, Despoina Kerselidou, Dimitrios Koutsoubaris, Elena Constantinou, George Malamas, Dimitrios A. Garyfallos and Eudoxia G. Ηatzivassiliou
    Citation: Journal of Biological Research-Thessaloniki 2020 27:7
  34. Zika virus (ZIKV) is a newly emergent relative of the Flaviviridae family and linked to dengue (DENV) and Chikungunya (CHIVKV). ZIKV is one of the rising pathogens promptly surpassing geographical borders. ZIK...

    Authors: Syeda Sidra Kazmi, Waqar Ali, Nousheen Bibi and Faisal Nouroz
    Citation: Journal of Biological Research-Thessaloniki 2020 27:5
  35. Diabetes is regarded as an epidemiological threat for the twenty-first century. Phytochemicals with known pharmaceutical properties have gained interest in the field of alleviating secondary complications of d...

    Authors: Ioannis Margaritis, Katerina Angelopoulou, Sophia Lavrentiadou, Ilias C. Mavrovouniotis, Maria Tsantarliotou, Ioannis Taitzoglou, Alexandros Theodoridis, Aristidis Veskoukis, Efthalia Kerasioti, Dimitrios Kouretas and Ioannis Zervos
    Citation: Journal of Biological Research-Thessaloniki 2020 27:4
  36. Bisphosphonates (BPs) are forceful inhibitors of osteoclast-mediated bone resorption. Long-term BP use is associated with multiple rare but severe adverse effects. The objective of this study was to investigat...

    Authors: Papamitsou Theodora, Papakoulas Apostolos, Papaliagkas Vasileios, Karachrysafi Sofia, Dietrich Eva-Maria and Sioga Antonia
    Citation: Journal of Biological Research-Thessaloniki 2020 27:2
  37. The fuel ethanol industry has made tremendous progress in the last decades. Ethanol can be obtained by fermentation using a variety of biomass materials as the feedstocks. However, few studies have been conduc...

    Authors: Yujin Cao, Hui Mu, Jing Guo, Hui Liu, Rubing Zhang, Wei Liu, Mo Xian and Huizhou Liu
    Citation: Journal of Biological Research-Thessaloniki 2020 27:1
  38. In Epirus, Greece, orchids have been traditionally harvested for the production of salep, a beverage made from their tubers. Over-collection of orchids for salep is believed to be a growing threat to wild spec...

    Authors: Martha Charitonidou, Kalliopi Stara, Konstantinos Kougioumoutzis and John M. Halley
    Citation: Journal of Biological Research-Thessaloniki 2019 26:18
  39. In the years of personalized (or precision) medicine the ‘omics’ methodologies in biomedical sciences—genomics, transcriptomics, proteomics and metabolomics—are helping researchers to detect quantifiable biolo...

    Authors: Katerina R. Katsani and Dimitra Sakellari
    Citation: Journal of Biological Research-Thessaloniki 2019 26:17
  40. MT1-MMP is a cell-surface enzyme whose regulation of pro-MMP-2 and ERK activation position it as a key facilitator of ECM remodelling and cell migration. These processes are modulated by endogenous MMP inhibit...

    Authors: Jessica A. Willson, Bradley S. Bork, Carlie A. Muir and Sashko Damjanovski
    Citation: Journal of Biological Research-Thessaloniki 2019 26:16
  41. Amyloid-β (Aβ)-induced neurotoxicity is a major pathological mechanism of Alzheimer’s disease (AD). Tanshinone IIA (Tan IIA), extracted from traditional Chinese herb Radix salvia miltiorrhiza, possesses anti-oxid...

    Authors: Lijiao Geng, Wei Liu and Yong Chen
    Citation: Journal of Biological Research-Thessaloniki 2019 26:15
  42. Comprehensively detailed information on population dynamics for benthic species is crucial since potential admixture of individuals could shift the genetic subdivision and age structure during a full breeding ...

    Authors: Georgios A. Gkafas, Marianthi Hatziioannou, Emmanouil E. Malandrakis, Costas S. Tsigenopoulos, Ioannis T. Karapanagiotidis, Elena Mente, Dimitrios Vafidis and Athanasios Exadactylos
    Citation: Journal of Biological Research-Thessaloniki 2019 26:14
  43. The Kastellorizo island group (in the Dodecanese, Greece) is situated in the southeast corner of the Aegean Archipelago. It consists of twenty islets, of which the three largest (Kastellorizo, Ro and Strongyli...

    Authors: Moisis Mylonas, Katerina Vardinoyannis and Nikos Poulakakis
    Citation: Journal of Biological Research-Thessaloniki 2019 26:13
  44. Exploring species richness and turnover patterns and their drivers can provide new insights into underlying mechanisms shaping community assembly, with significant implications for biodiversity conservation. H...

    Authors: Maria Lazarina, Athanasios S. Kallimanis, Panayotis Dimopoulos, Maria Psaralexi, Danai-Eleni Michailidou and Stefanos P. Sgardelis
    Citation: Journal of Biological Research-Thessaloniki 2019 26:12