Skip to main content

Table 3 Physicochemical properties of selected potential biomarkers using ProtParam, ProtScale, and PeptideMass tools

From: A systematic simulation-based meta-analytical framework for prediction of physiological biomarkers in alopecia

Potential biomarkers Formula Total amino Acids Molecular weight Theoretical pI Ext. coefficient Estimated half-life (h) Instability index (II) Hydropathicity (GRAVY) Monoisotopic mass
WIF1 C1813H2808N518O524S40 379 415,27.80 7.84 46,920 30.0 54.70 − 0.264 41,499.78
SPON1 C3929H6190N1114O1225S73 807 90,973.40 5.85 149,205 30.0 61.34 − 0.604 90,913.59
LYZ C719H1146N220O207S11 148 16,537.00 9.38 36,940 30.0 27.71 − 0.195 16,526.28
GPRC5B C2072H3244N526O542S23 6407 44,933.13 8.06 65,930 30.0 42.45 0.52 44,903.60
PTPRE C3622H5651N979O1040S34 700 80,641.69 6.57 97,010 30.0 35.24 − 0.342 80,589.99
ZFP36L2 C2219H3438N650O702S19 494 51,062.78 8.52 15,900 30.0 69.83 − 0.387 51,030.80
HBB C729H1128N196O202S4 147 15,998.41 6.74 15,595 30.0 6.16 0.014 15,988.29
HBB C497H770N134O146S2 101 11,022.51 6.03 12,490 7.2 1.52 − 0.239 11,015.64
PHF15 C3798H6018N1078O1203S43 789 87,408.65 5.15 92,360 30.0 57.12 − 0.639 87,353.08
LMCD1 C1782H2822N502O539S29 365 40,832.79 8.27 53,860 30.0 47.12 − 0.565 40,806.07
KRT35 C2144H3464N620O715S31 455 50,360.67 4.85 37,245 30.0 61.99 − 0.445 50,328.51
VAV3 C3857H6055N1055O1148S35 753 86,695.99 6.41 88,920 30.0 42.18 − 0.567 86,640.81