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Table 2 Expression of cell adhesion molecules in benign SGTs

From: Cell adhesion molecules’ altered profile in benign and malignant salivary gland tumors. The paradigm of beta4-integrin, desmoglein-2, ICAM-1 and CD44s

CAMs

Positivity (%)

Pattern of staining

Topography and intensity of staining

Luminal cells

Non-luminal cells

Cells in Islands

Solitary neoplastic stromal cells

Dsg-2

III (30/30)

C (mainly)/M

++

+

++

Beta4-integrin

III (30/30)

M (mainly)/C

++

++

++

++

CD44s

III (30/30)

M

+

++

++

ICAM-1

III (8/30)

II (13/30)

I (9/30)

M: (Luminal surface mainly)/C

+

+

+

Myoepitheliomas

CAM

Positivity

Pattern of staining

Intensity of staining

   

Dsg-2

III (2/2)

C

++

   

Beta4-integrin

III (2/2)

M/C

+++

   

HCAM (CD44s)

II: 2/2

M

++

   

ICAM-1

III: 1/2

I: 1/2

C

+

++

   

Oncocytomas

CAM

Positivity

Pattern of staining

Intensity of staining

   

Dsg-2

III: 2/2

C

++

   

Beta4-integrin

III: 2/2

M/C

+++

   

HCAM (CD44s)

III: 2/2

M

+

   

ICAM-1

C

+