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Table 2 Expression of cell adhesion molecules in benign SGTs

From: Cell adhesion molecules’ altered profile in benign and malignant salivary gland tumors. The paradigm of beta4-integrin, desmoglein-2, ICAM-1 and CD44s

CAMs Positivity (%) Pattern of staining Topography and intensity of staining
Luminal cells Non-luminal cells Cells in Islands Solitary neoplastic stromal cells
Dsg-2 III (30/30) C (mainly)/M ++ + ++
Beta4-integrin III (30/30) M (mainly)/C ++ ++ ++ ++
CD44s III (30/30) M + ++ ++
ICAM-1 III (8/30)
II (13/30)
I (9/30)
M: (Luminal surface mainly)/C + + +
Myoepitheliomas
CAM Positivity Pattern of staining Intensity of staining    
Dsg-2 III (2/2) C ++    
Beta4-integrin III (2/2) M/C +++    
HCAM (CD44s) II: 2/2 M ++    
ICAM-1 III: 1/2
I: 1/2
C +
++
   
Oncocytomas
CAM Positivity Pattern of staining Intensity of staining    
Dsg-2 III: 2/2 C ++    
Beta4-integrin III: 2/2 M/C +++    
HCAM (CD44s) III: 2/2 M +    
ICAM-1 C +