Fig. 7

CircCTNNA1 knockdown inhibited CRC tumorigenesis in vivo. SW620 cells transfected with sh-con or sh-circCTNNA1 were injected into nude mice. Tumor volume (a) and tumor weight (b) in each group were determined. c The expression levels of circCTNNA1, miR-363-3p and CXCL5 in the tumor tissues of each group were detected using qRT-PCR. d The protein expression of CXCL5 in the tumor tissues of each group was measured using WB analysis. *p < 0.05, ***p < 0.001