Fig. 12

Active site residues & drug binding motifs of NSP3. a, b Two different surfaces showing drug binding motifs in close association with active site residues of the enzyme. Here Anprenavir, Darunavir and Saquinavir targeted active site residue VAL253 in a pocket. 478-Amprenavir; 017-Darunavir; RIM Rimantadine, ROC Saquinavir