Fig. 4
MMP2 overexpression overturned the effects of circ_0000620 silence on the progression of GC cells. A The expression of MMP2 in HGC27 and AGS cells transfected with vector or MMP2 was detected by western blot. B-H HGC27 and AGS cells were transfected with sh-NC + vector, sh-circ_0000620 + vector or sh-circ_0000620 + MMP2 for 36Â h. CCK-8 assay, colony formation assay, wound healing assay, transwell assay and tube formation assay were conducted for the detection of cell viability (B), colony formation (C), cell migratory ability (D), cell invasive ability (E) and tube formation capacity (F), respectively. G, H The expression of MMP2, E-cad and N-cad was examined by western blot assay. Three repetitions were performed in each experiment, with three parallels every time. *p < 0.05